DNA computing on a chip

DNA computing on a chip.

Fault Tolerant DNA Computing Based on ‎Digital Microfluidic Biochips

   Historically, DNA molecules have been known as the building blocks of life, later on in 1994, Leonard Adelman introduced a technique to utilize DNA molecules for a new kind of computation. According to the massive parallelism, huge storage capacity and the ability of using the DNA molecules inside the living tissue, this type of computation is applied in many application areas such as me...

Dna Analysis Systems on a Chip

This paper presents a review of microfabricated systems for genetic diagnostics. Genetic diagnostics are powerful technology drivers and excellent candidate applications for miniaturization technologies because the demand for inexpensive genetic information is essentially unlimited, and the cost and time for the diagnostic decreases with sample volume. Processing of DNA molecules in the microsc...

Analyzing DNA-protein interactions on a chip

Gene expression is regulated by multi-protein complexes binding to short non-coding regions of genomic DNA, called cisregulatory elements. A long-term goal of genomics is to identify and annotate all essential elements of the genome. Most coding elements of the genome have been identified and annotated; however, most regulatory elements have not. This chapter describes a method for the high thr...

DNA chip replication for a personalized DNA chip.

We report the replication technology of DNA chip using by sequence specific localization of nucleic acids via hybridization and electric transfer of the nucleic acids onto a new substrate without losing their array information. The denatured DNA fragments are first spotted and UV-cross-linked on a nylon membrane. The membrane is then immersed and hybridized in a DNA mixture solution that contai...